Error: 1073759778, Severity: 1, State: 0 Error: 1073759806, Severity: 1, State: 0

You may find below error message in SQL Server Error Log typically adjutant to SQL Mail session start up messages.

Error: 1073759778, Severity: 1, State: 0
Error: 1073759806, Severity: 1, State: 0

These are Severity: 1 error which means they are for information purpose only. These messages are logged because SQL Mail started with xp_startmail which is unnecessary in SQL 2000. SQL Mail automatically starts when you run xp_sendmail in SQL 2000.

Below messages are from a SQL 2000 SP4 Error Log which for same reason we discussed here:

Error: 1073759778, Severity: 1, State: 0
SQL Mail session started..
Using 'sqlmap70.dll' version '2000.80.2039' to execute extended stored procedure 'xp_sendmail'. Error: 1073759806, Severity: 1, State: 0
Starting SQL Mail session....
Using 'xpsqlbot.dll' version '2000.80.2039' to execute extended stored procedure 'xp_qv'.

Proposed corrective action:

Short Term: No action needed. You can safely ignore this message.
Long Term: Avoid using xp_startmail as xp_sendmail will initiate SQL Mail anyway. Best approach is not using SQL Mail anyway if possibly by moving to a new version of SQL Server.

Please Note:
This post is relevant to SQL 2000 using SQL Mail.